In vitro antioxidant and antithrombotic activity of hemidesmus indicus l r. Hemidesmus indicus is an important medicinal plant and extensively used in ayurvedic and unani system of medicine. Mitochondrial pathway mediates the antileukemic effects of. Roots 2391 23 21 19 17 15 24 3j 29 28 1 rh 1a r me 0 or a. The leaves are opposite, shortpetioled, very variable, ellipticoblong to linearlanceolate. Antinociceptive activity of alcoholic extract of hemidesmus indicus r. This methoxybenzaldehyde was shown to have inhibitory potential against diphenolase activity of the tyrosinase. Asclepiadaceae is a well known drug in ayurveda system of medicine. The stem is numerous, slender, terete, thickened at the nodes. Request pdf antioxidant activity of roots of hemidesmus indicus the antioxidant property of roots of hemidesmus indicus l. The present study suggests that hemidesmus indicus has protective activity against arthritis and the activity might be attributed to presence of terpenoid in hydroalcoholic extract, as well as in.
Antiasthmatic activity of roots of hemidesmus indicus r. Indian sarsaparilla gymnema sylvestre hemidesmus indicus. In the present study, antioxidant activity of methanolic extract. Hemidesmus hemidesmus indicus root is regarded in ayurvedic medicine as a depurative and tonic. It is an effective antiinflammatory, direutic and vulnerary. The aim of the article is to investigate the antiarthritic efficacy of hemidesmus indicus in vitro. Pharmacological interventions on oxidative stress and plasma. University of baroda, vadodara 390002 gujarat, india 2 radiology department, ssg. Apr 14, 2015 latin binomial gymnema sylvestre hemidesmus indicus common name indian sarsaparilla, nunnari, mesasrngi, cowplant family asclepiadaceae 1 parts used root, bark, stem 1, leaf 8 qualities bitter 9 active constituents triterpenoidic saponins, hypoglycaemic activity 3 gymnemic acids, acidic glycosides, and anthroquinones 9, gymnema saponins, polypeptide, gurmarin 10, resins. Highfat diet induced changes in average body weight and oxidative stress and elevated levels of plasma lipid profile in rats. The larvicidal effect of aqueous extracts of hemidesmus indicus roots, gymnema sylvestre and eclipta prostrata leaves were tested against culex quinquefasciatus larvae at the concentrations of 1, 2, 3, 4and 5% up to three days. Jul 15, 2014 take the roots of hemidesmus indicus, rub on stone.
Antioxidant activity of hemidesmus indicus pdf the methanolic extract of hemidesmus indicus l asclepiadaceae roots was found to inhibit lipid peroxidation and scavenge hydroxyl and superoxide. Nov 14, 2005 the extract of hemidesmus indicus at doses of 25, 50 and 100 mgkg, showed antinociceptive activity in all the models for nociception and the effect was found to be dosedependent. Antioxidant activity of roots of hemidesmus indicus. Hemidesmus indicus root extract incubated with viper venom antagonized coagulant and haemorrhagic activity alam et al. Used in a similar fashion to regular sarsaparilla, indian sarsaparilla has slightly different applications. Cytotoxicity and antioxidant activity of 52, 4dimethylbenzyl pyrrolidin2one. Among these, the antioxidant and antimicrobial activity was well documented. Opposite, elliptic oblong to linearlanceolate, variegated with white above. The percentage of activated caspase3 cells in non treated cultures was about 3% which was increased to 9% in cells treated with hemidesmus p hemidesmus indicus l r. Ayurveda medicines with hemidesmus indicus as ingredient sarivadyasavam useful in gout, skin diseases mathala rasayanam useful in cough, cold, asthma, bleeding disorders.
Larval mortality was 100% with the use of 5% concentration of root extract of h. Root organs of hemidesmus indicus are traditionally known for multipurpose medicinal applications. Hemidesmus indicus belongs to apocynacea dogbane family. Asclepiadaceae is a climbing plant, with twining, woody, slender stems, and opposite, petiolate leaves, which are entire, smooth, shining.
Medicinal uses of anantmool or indian sarsaparilla bimbima. Antiarthritis activity of roots of hemidesmus indicus r. Journal of chemical and pharmaceutical research, 2017, 94. Jcprc5 50 some aspects of investigation of the indian medicinal plant hemidesmus indicus r.
The root bark also possess antioxidant activity ravishankara et al. Gum diseases, tooth problems crush the leaves of the plant and put under the teeth. Although other species of this variety has been reported for its standards7 this has been the complete pharmacognostic validation of this variety which may be used for formulation development in future. Antioxidant effects of roots of clerodendrum serratum linn. University of calcutta, 92 acharya profulla road, calcutta 700009 india. Evaluating tyrosinase monophenolase inhibitory activity. From the roots of hemidesmus indicus, one new condensed phenylpropanoid glucoside and three new pregnenolone glycosides, named hemidesmosides ac, were isolated along with one known related compound, plocoside a. The extract decreased the number of acetic acidinduced abdominal constrictions in mice and the values were found to be significant at doses level tested fig. A condensed phenylpropanoid glucoside and pregnane. Hemidesmus indicus, specifically its roots extract to retain all the potential benefits with a new taste and flavor. Sariva, sarbia, ontomulo, naruninti nannari, tygade beru, anantvel, durivel family name. Antioxidant activity in the study conducted by ravishankara and coworkers methanolic extract of hemidesmus indicus roots showed a concentrationdose dependent inhibition of. Periplocaceae is being used widely in ayurvedic medicine.
The antioxidant properties of free and encapsulated root extract were determined by dpph, superoxide and. Hemidesmus indicus protects against ethanolinduced liver toxicity. Indian sarsaparilla hemidesmus indicus magarbu or anantmul. Hemidesmus indicus is commonly known as indian sarasaparilla a perennial climber and growing widely in upper gangetic plains and eastwards of bengal and from central to south india3. Rehmannia complex contains rehmannia, bupleurum, hemidesmus and feverfew that work to support general. Indian sarsaparilla hemidesmus indicus otherwise known as false sarsaparilla, sughandi root or the eternal root, is the indian counterpart to american sarsaparilla smilax spp.
Hemidesmus indicus is known in ayurvedic medicine as sugandi, and it has been valued for its medicinal properties for almost a thousand years. Antioxidant effect of hemidesmus indicus on ethanolinduced hepatotoxicity in rats. The extract decreased the number of acetic acidinduced abdominal constrictions in mice and the values were found to be significant at doses level tested. Larvicidal effect of hemidesmus indicus, gymnema sylvestre, and eclipta. Male wistar rats were divided into 6 groups n6group and fed with a standard diet control, highfat diet hfd, highfat diet supplemented with different extracts and positive control for 9 weeks. Alleviates contamination of skin, skin diseases, itches, boils, purifies blood. Mediherb products potential herbdrug interactions chart pdf kerry bones essentials books. Combine with gotu kola complex tablets to provide antioxidant activity. Hemidesmus indicus root by pharmacognostically as per who guidelines. Evaluation of antioxidant properties of 20 medicinal plant. The record derives from tropicos data supplied on 20120418 which reports it as an accepted name record 2609794 with original publication details. Angiosperm diversity assessment of chitrakootthe legendary place of vindhyan range, india journal of economic and taxonomic botany 38. The herbal extract has promote the release of igg by lymphocytes and also the ada activity kainthla r p, kashyap effect of hemidesmus indicus anantmool extract on igg production and adenosine deaminase activity of human lymphocytes in vitro. Antioxidant activity in the study conducted by ravishankara and coworkers methanolic extract of hemidesmus indicus roots showed a concentrationdose dependent inhibition of 1, 1diphenyl2picryl hydrazyl dpph radical, superoxide radicals and moderate nitric oxide scavenging activity due to the presence of polar components.
Hemidesmus indicus benefits, usage, dose, side effects. Plastic surgery, couching a form usess cataract surgerypuncturing to release fluids in abdomen, treatment of anal fistulas, treating fractures, amputations, cesarean sections and. Cleavage of the ester linkage generated a fragment at mlz 129. Evaluation of antioxidant properties of root bark of hemidesmus. Plant details information about hemidesmus indicus plant. Roots are useful in hemidesmus indicus plant is a slender, twining or prostrate perennial shrub with cylindrical stems. The root extracts of hemidesmus indicus in different ratios of petroleum ether and ethyl acetate, tests have shown significant zone of inhibition to all. Hemidesmus indicus is a pharmacologically important plant. Studies on steroids in cultured tissues and mature plant of h. Antibacterial activity of the root extracts of hemidesmus. Formulation of a carbonated herbal health drink with. The in vitro experiment by the disc diffusion method established that hemidesmus indicus root extracts posses a bioactive compound, which inhibits the growth of the microorganisms. Anantamul, sariva, indian sarsaparilla is a wellknown indian plant 1012. Common names are anantamula, ananthamoola, east indian sarsaparilla, false sarsaparilla.
Antimicrobial activity of hemidesmus indicus, ficus. Asclepiadaceae health and benefits of indian sarsaparilla. Br article pdf available in journal of ethnopharmacology 8723. The extract of hemidesmus indicus at doses of 25, 50 and 100 mgkg, showed antinociceptive activity in all the models for nociception and the effect was found to be dosedependent. Evaluation of antioxidant properties of root bark of. Asclepiadaceae is a climbing plant, with twining, woody, slender stems, and opposite, petiolate leaves, which are entire, smooth, shining, and of a firm consistence. It is a slender, laticiferous, twining, sometimes prostrate or semierect shrub. The bioactive and therapeutic potential of hemidesmus indicus r. All these properties come in handy to purify the contamination of blood which is the principle behind many skin disorders and skin allergies. After administration of 5 mgkg, 50 mgkg, 500 mgkg and until 2000 mgkg dose of different extracts of h. Hemidesmus indicus, indian sarsaparilla, is a species of plant that is found in south asia. Ccl 4 and paracetamol induced hepatic damage can be cured upto an extent too by h. In ayurveda, it has been used medicinally to treat stomach problems, to cure rashes and to calm the mind and induce trance states and deep meditation.
Br chemical constituents and antidiabetic activity avijit banerji1,2, julie banerji2, manosi das1, dhiren mondol1 and jayram hazra1. Pdf in vitro antioxidant and antithrombotic activity of. Hemidesmus indicus is a perennial, fastgrowing thin creeper vine that sends tendrils out at every node to cling to the surrounding vegetation for stability and support. Phytochemical investigation of hemidesmus indicus r. Centre of advanced studies on natural products corporate author. The study was done to formulate a drink from an old medicinal herb and retain all the potential benefits with a new taste and flavor. Hemidesmus indicus is used to make beverages and also used in traditional medicine. Latin binomial gymnema sylvestre hemidesmus indicus common name indian sarsaparilla, nunnari, mesasrngi, cowplant family asclepiadaceae 1 parts used root, bark, stem 1, leaf 8 qualities bitter 9 active constituents triterpenoidic saponins, hypoglycaemic activity 3 gymnemic acids, acidic glycosides, and anthroquinones 9, gymnema saponins, polypeptide. Evaluation of phytochemical composition and antioxidative. The leaves vary much in size and shape, some being linear and acute, others broadlanceolate, and others again oval or ovate.
Hemidesmus indicus mother tincture buy online at best prices with free delivery all over india. It has been used to treat chronic rheumatism, kidney and skin disorders and constitutional debility. Hair growth, alopecia, hair fall take 2 grams hemidesmus indicus root powder, 23 times a day with water. Or you can apply the milky exude of the plant mixed with honey.
The leaves are very slender, smooth and oval shaped, closely resembling blades of grass, and they maintain a uniform shiny dark green color throughout the year. Antinociceptive activity of alcoholic extract of hemidesmus. The eternal root top 5 health benefits of indian sarsaparilla. The plasma recalcification time was also delayed significantly by the intravenous administration of the root extract. Take the roots of hemidesmus indicus, rub on stone.
Mediherb products potential herb drug interactions chart pdf kerry bones essentials books. The assay was based on the capacity of the methanolic extract of h. Anantmul in rats alka mehta 1, neeraj k sethiya 1, chetan mehta 2, gb shah 3 1 pharmacy department, faculty of technology and engineering kalabhavan, the m. It is a slender, laticiferous, twining, sometimes prostrate or semierect shrub call us.
Cytotoxic effects of a decoction of nigella sativa, hemidesmus indicus and smilax glabra on human hepatoma hepg2 cells. In vitro antioxidant and antithrombotic activity of. Title handbook of ayurvedic medicinal plants publication author kapoor. Sep 01, 2012 effect of hemidesmus indicus anantmool extract on igg production and adenosine deaminase activity of human lymphocytes in vitro. Hemidesmus indicus affects caspase3 but not caspase8 activity and activates parp caspase3 activity was significantly increased in cells treated with hemidesmus 0. Antiinflammatory and antihyperlipidemic activities of root extracts of. Medicinal plants are being widely used, either as single drug or in combination in health care delivery system. Hemidesmus indicus definition of hemidesmus indicus by. Enhancement in the absorption of water and electrolytes from rat intestine by hemidesmus indicus r. For this an herbal drink was formulated and its quality ascertained. Tlc finger printing profile of methanolic extract of h. Ayurvedic and modern aspects of sariva hemidesmus indicus r. Year 2001 isbn 0849329299 description a very detailed book on some of the key ayurvedic herbs, giving both technical and nontechnical information on each plant.
The antimicrobial activity of hemidesmus indicus, ficus bengalensis and pterocarpus marsupium roxb was evaluated against pathogenic bacteria stahylococcus aureus, pseudomonas aeruginosa and klebsiella pneumonia in an in vitro condition. The antioxidant properties of free and encapsulated root extract were determined by dpph, superoxide and hydroxyl radical scavenging assays. Antioxidant and antihyperlipidemic activity of hemidesmus. In the first part of the study, syrup was prepared from the raw roots of the herb with addition of acids and flavors. It is a climbing plant that grows almost all over india. Indian herbal medicines in the treatment of liver diseases. The herb, also known as false sarsaparilla, is also made into a tonic that is used to improve mental function, and it is employed in treatments to help ease skin infections, rheumatism and urinary problems. Antimicrobial activity anti carcinogenic and cytotoxic potential. Ayurvedic medicine makes use of the herb hemidesmus indicus in several different ways, most notably as a diuretic and a blood purifier. Hemidesmus indicus, sariva, asclepiadaceae, indian sarsaparilla created date. The history of its medicinal importance dates back to ancient times.
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